Calcitonin gene-related peptide in newly diagnosed idiopathic intracranial hypertension: a prospective, cross-sectional, case-control study of cerebrospinal fluid and plasma

Table 3 Sub-analyses of CGRP levels in plasma and CSF depending on headache existence, migraine phenotype, and chronicity

	Plasma (pmol/L)	p-value	CSF (pmol/L)	p-value
Comparison 1, mean (± SD)
IIH with headache	157 ± 87, n = 80		48 ± 16, n = 75
Non-IIH with chronic migraine	159 ± 88, n = 28		49 ± 14, n = 26
Healthy controls	167 ± 66, n = 36	0.834	47 ± 12, n = 31	0.836
Comparison 2, median (IQR)
IIH with headache	160 (118–189), n = 80		45 (41–63), n = 75
IIH without headache	129 (87–205), n = 7	0.708	47 (37–58), n = 7	0.752
Comparison 3, mean (± SD)
IIH with chronic migraine	174 ± 92, n = 26		48 ± 16, n = 25
Healthy controls without migraine	168 ± 66, n = 30	0.803	46 ± 13, n = 26	0.755

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